FESS is more appropriate than long term / repeated antibiotics for chronic sinusitis

2026-06-01T10:16:35+09:30

The results of the MACRO trial should provide clinicians with confidence in offering surgery as a treatment option to adults with chronic rhinosinusitis without adequate response to intranasal steroids and rinses. The MACRO trial findings indicate that long-term macrolides such as clarithromycin should not be used routinely in patients in primary care or secondary care, especially when the endotype is not determined. Further details about the article published by Professors Carl Philpott and Claire Hopkins is available  from the link https://hospitalhealthcare.com/specialisms/respiratory/managing-chronic-rhinosinusitis-expert-insight-from-the-macro-trial/ Patients can discuss with the Adelaide ENT Surgeons about the findings from the MACRO Trial. Professor Eng Ooi